David E. Nichols

Professor of medicinal chemistry and molecular pharmacology in the School of Pharmacy (Purdue University/ Mark Simons)

David E. Nichols, PhD is currently an Adjunct Professor in the Eshelman School of Pharmacy at the University of North Carolina, Chapel Hill, NC.  He is a Distinguished Professor Emeritus at the Purdue University College of Pharmacy, and was the Robert C. and Charlotte P. Anderson Chair in Pharmacology, where he carried out teaching and research for 38 years prior to his retirement in 2012.  The focus of his graduate training, beginning in 1969, and of most of his research subsequent to receiving his doctorate in 1973 was the investigation of the relationship between molecular structure and the action of various substances that modify behavior.  A major focus of his research was on substances known as hallucinogens, known more popularly as psychedelics.  Widely published in the scientific literature and internationally recognized for his research on centrally active drugs, he has studied all of the major classes of psychedelic agents, including LSD and other lysergic acid derivatives, psilocybin and the tryptamines, and phenethylamines related to mescaline.  Among scientists, he is recognized as one of the foremost international experts on the medicinal chemistry of psychedelics.

Title of talk: Structure-Activity Relationships of LSD Analogues